Turkey Tail Research

A significant amount of impressive turkey tail research has been done to date. This research explores the therapeutic value of the turkey tail mushroom for a variety of different health conditions as well as general health and wellness.

These are just a few of those studies. More is being done every day. Check back regularly for updates. 


Polysaccharide krestin is a novel TLR2 agonist that mediates inhibition of tumor growth via stimulation of CD8 T cells and NK cells https://pubmed.ncbi.nlm.nih.gov/21068144/ 

Antitumor effect of PSK at a distant site: inductions of interleukin-8-like factor and macrophage chemotactic factor in murine tumor https://pubmed.ncbi.nlm.nih.gov/2126000/ 

Coriolus Versicolor and Ganoderma Lucidum Related Natural Products as an Adjunct Therapy for Cancers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials https://pubmed.ncbi.nlm.nih.gov/31333449/ 

Effects of Medicinal Fungi-Derived β-Glucan on Tumor Progression https://pubmed.ncbi.nlm.nih.gov/33806255/ 

Polysaccharide K and Coriolus versicolor extracts for lung cancer: a systematic review https://pubmed.ncbi.nlm.nih.gov/25784670/ 

PSK may suppress CD57(+) T cells to improve survival of advanced gastric cancer patients https://pubmed.ncbi.nlm.nih.gov/20229169/ 

Phase 1 Clinical Trial of Trametes versicolor in Women with Breast Cancer https://pubmed.ncbi.nlm.nih.gov/22701186/

Purification, characterization, and antitumor activity of a novel glucan from the fruiting bodies of Coriolus Versicolor https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298263/ 

Immune Support

Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684115/ 

Antigenotoxic Effect of Trametes spp. Extracts against DNA Damage on Human Peripheral White Blood Cells https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517545/

PSP activates monocytes in resting human peripheral blood mononuclear cells: immunomodulatory implications for cancer treatment https://pubmed.ncbi.nlm.nih.gov/23497877/ 

Preclinical and clinical studies of Coriolus versicolor polysaccharopeptide as an immunotherapeutic in China https://pubmed.ncbi.nlm.nih.gov/28595034/

The lignicolous fungus Trametes versicolor (L.) Lloyd (1920): a promising natural source of antiradical and AChE inhibitory agents https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010034/ 

The mycelium of the Trametes versicolor (Turkey tail) mushroom and its fermented substrate each show potent and complementary immune activating properties in vitro https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889544/ 

Gut Health

Effects of polysaccharopeptide from Trametes versicolor and amoxicillin on the gut microbiome of healthy volunteers: a randomized clinical trial https://pubmed.ncbi.nlm.nih.gov/25006989/ 

A Critical Review on Health Promoting Benefits of Edible Mushrooms through Gut Microbiota https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618583/ 

Mushroom Polysaccharides: Chemistry and Antiobesity, Antidiabetes, Anticancer, and Antibiotic Properties in Cells, Rodents, and Humans https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302426/

Antioxidant Properties

Assessment of Bioactive Compounds and Antioxidant Activity of Turkey Tail Medicinal Mushroom Trametes versicolor (Agaricomycetes) http://www.dl.begellhouse.com/journals/708ae68d64b17c52,3d8e7b4f6342518e,4675f12b644a5c81.html 

Mycochemical Investigation of the Turkey Tail Medicinal Mushroom Trametes versicolor (Higher Basidiomycetes): A Potential Application of the Isolated Compounds in Documented Pharmacological Studies http://www.dl.begellhouse.com/journals/708ae68d64b17c52,7b35b5ed6bb0a817,042641d17ec1fb0f.html 

Turkey Tail Medicinal Mushroom, Trametes versicolor (Agaricomycetes), Crude Exopolysaccharides with Antioxidative Activity http://www.dl.begellhouse.com/journals/708ae68d64b17c52,358d19d227c8633b,619a4f915cd02626.html 

Extracellular Polysaccharopeptides from Fermented Turkey Tail Medicinal Mushroom, Trametes versicolor (Agaricomycetes), Mitigate Oxidative Stress, Hyperglycemia, and Hyperlipidemia in Rats with Type 2 Diabetes Mellitus http://www.dl.begellhouse.com/journals/708ae68d64b17c52,489762826cea4201,39339ece262c3632.html